Does IFOSFAMIDE Cause Splenomegaly? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Splenomegaly have been filed in association with IFOSFAMIDE (IFEX). This represents 0.1% of all adverse event reports for IFOSFAMIDE.
17
Reports of Splenomegaly with IFOSFAMIDE
0.1%
of all IFOSFAMIDE reports
5
Deaths
3
Hospitalizations
How Dangerous Is Splenomegaly From IFOSFAMIDE?
Of the 17 reports, 5 (29.4%) resulted in death, 3 (17.6%) required hospitalization, and 1 (5.9%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IFOSFAMIDE. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does IFOSFAMIDE Cause?
Off label use (2,281)
Febrile neutropenia (2,225)
Disease progression (1,912)
Neutropenia (1,509)
Drug ineffective (1,331)
Thrombocytopenia (1,227)
Anaemia (1,067)
Product use in unapproved indication (890)
Pyrexia (752)
Sepsis (712)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which IFOSFAMIDE Alternatives Have Lower Splenomegaly Risk?
IFOSFAMIDE vs IGURATIMOD
IFOSFAMIDE vs ILOPERIDONE
IFOSFAMIDE vs ILOPROST
IFOSFAMIDE vs IMATINIB
IFOSFAMIDE vs IMBRUVICA