Does INTERFERON BETA-1A Cause Necrosis? 45 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 45 reports of Necrosis have been filed in association with INTERFERON BETA-1A (Avonex). This represents 0.1% of all adverse event reports for INTERFERON BETA-1A.
45
Reports of Necrosis with INTERFERON BETA-1A
0.1%
of all INTERFERON BETA-1A reports
2
Deaths
10
Hospitalizations
How Dangerous Is Necrosis From INTERFERON BETA-1A?
Of the 45 reports, 2 (4.4%) resulted in death, 10 (22.2%) required hospitalization, and 1 (2.2%) were considered life-threatening.
Is Necrosis Listed in the Official Label?
Yes, Necrosis is listed as a known adverse reaction in the official FDA drug label for INTERFERON BETA-1A.
What Other Side Effects Does INTERFERON BETA-1A Cause?
Multiple sclerosis relapse (5,931)
Influenza like illness (4,475)
Memory impairment (3,468)
Multiple sclerosis (3,412)
Fatigue (3,164)
Fall (3,128)
Gait disturbance (3,031)
Death (2,766)
Pain (2,692)
Headache (2,533)
What Other Drugs Cause Necrosis?
METHOTREXATE (155)
PREDNISONE (143)
TACROLIMUS (120)
ADALIMUMAB (119)
MYCOPHENOLATE MOFETIL (101)
CYCLOPHOSPHAMIDE (97)
RITUXIMAB (97)
GLATIRAMER (84)
PREDNISOLONE (83)
METHYLPREDNISOLONE (76)
Which INTERFERON BETA-1A Alternatives Have Lower Necrosis Risk?
INTERFERON BETA-1A vs INTERFERON BETA-1B
INTERFERON BETA-1A vs INTERFERON GAMMA
INTERFERON BETA-1A vs INTERFERON GAMMA-1B
INTERFERON BETA-1A vs INVEGA
INTERFERON BETA-1A vs INVEGA SUSTENNA