Does IPILIMUMAB Cause Large intestine perforation? 129 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 129 reports of Large intestine perforation have been filed in association with IPILIMUMAB (YERVOY). This represents 0.4% of all adverse event reports for IPILIMUMAB.
129
Reports of Large intestine perforation with IPILIMUMAB
0.4%
of all IPILIMUMAB reports
48
Deaths
94
Hospitalizations
How Dangerous Is Large intestine perforation From IPILIMUMAB?
Of the 129 reports, 48 (37.2%) resulted in death, 94 (72.9%) required hospitalization, and 32 (24.8%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IPILIMUMAB. However, 129 reports have been filed with the FAERS database.
What Other Side Effects Does IPILIMUMAB Cause?
Death (3,710)
Malignant neoplasm progression (3,296)
Diarrhoea (2,557)
Off label use (2,097)
Colitis (1,988)
Pyrexia (1,796)
Rash (1,556)
Fatigue (1,447)
Intentional product use issue (1,329)
Nausea (1,169)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which IPILIMUMAB Alternatives Have Lower Large intestine perforation Risk?
IPILIMUMAB vs IPRAGLIFLOZIN L-PROLINE
IPILIMUMAB vs IPRATROPIUM
IPILIMUMAB vs IPRATROPIUM\IPRATROPIUM ANHYDROUS
IPILIMUMAB vs IPTACOPAN
IPILIMUMAB vs IRBESARTAN