Does ISONIAZID Cause Encephalopathy? 93 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 93 reports of Encephalopathy have been filed in association with ISONIAZID (Isoniazid). This represents 1.2% of all adverse event reports for ISONIAZID.
93
Reports of Encephalopathy with ISONIAZID
1.2%
of all ISONIAZID reports
43
Deaths
74
Hospitalizations
How Dangerous Is Encephalopathy From ISONIAZID?
Of the 93 reports, 43 (46.2%) resulted in death, 74 (79.6%) required hospitalization, and 28 (30.1%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
Yes, Encephalopathy is listed as a known adverse reaction in the official FDA drug label for ISONIAZID.
What Other Side Effects Does ISONIAZID Cause?
Drug-induced liver injury (766)
Drug ineffective (607)
Drug reaction with eosinophilia and systemic symptoms (550)
Pyrexia (517)
Nausea (488)
Paradoxical drug reaction (433)
Off label use (406)
Drug resistance (367)
Hepatotoxicity (349)
Headache (324)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which ISONIAZID Alternatives Have Lower Encephalopathy Risk?
ISONIAZID vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISONIAZID vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID vs ISONIAZID\RIFAMPIN
ISONIAZID vs ISOPROPANOLAMINE
ISONIAZID vs ISOPROPYL ALCOHOL