Does JAKAVI Cause Splenomegaly? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Splenomegaly have been filed in association with JAKAVI. This represents 10.8% of all adverse event reports for JAKAVI.
16
Reports of Splenomegaly with JAKAVI
10.8%
of all JAKAVI reports
1
Deaths
5
Hospitalizations
How Dangerous Is Splenomegaly From JAKAVI?
Of the 16 reports, 1 (6.3%) resulted in death, 5 (31.3%) required hospitalization, and 1 (6.3%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for JAKAVI. However, 16 reports have been filed with the FAERS database.
What Other Side Effects Does JAKAVI Cause?
Death (30)
Platelet count decreased (22)
Anaemia (17)
Haemoglobin decreased (13)
Cardiac failure (9)
Dyspnoea (9)
Thrombocytopenia (9)
Pyrexia (8)
Fatigue (7)
Myelofibrosis (7)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which JAKAVI Alternatives Have Lower Splenomegaly Risk?
JAKAVI vs KETAMINE
JAKAVI vs KETOCONAZOLE
JAKAVI vs KETOPROFEN
JAKAVI vs KETOROLAC TROMETHAMINE
JAKAVI vs LABETALOL\LABETALOL