Does LAMIVUDINE Cause Splenomegaly? 75 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 75 reports of Splenomegaly have been filed in association with LAMIVUDINE (Lamivudine and Zidovudine). This represents 0.5% of all adverse event reports for LAMIVUDINE.
75
Reports of Splenomegaly with LAMIVUDINE
0.5%
of all LAMIVUDINE reports
11
Deaths
47
Hospitalizations
How Dangerous Is Splenomegaly From LAMIVUDINE?
Of the 75 reports, 11 (14.7%) resulted in death, 47 (62.7%) required hospitalization, and 1 (1.3%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
Yes, Splenomegaly is listed as a known adverse reaction in the official FDA drug label for LAMIVUDINE.
What Other Side Effects Does LAMIVUDINE Cause?
Foetal exposure during pregnancy (1,905)
Virologic failure (1,894)
Drug resistance (1,889)
Pathogen resistance (1,733)
Viral mutation identified (1,631)
Treatment failure (933)
Exposure during pregnancy (846)
Drug interaction (744)
Drug ineffective (726)
Immune reconstitution inflammatory syndrome (625)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which LAMIVUDINE Alternatives Have Lower Splenomegaly Risk?
LAMIVUDINE vs LAMIVUDINE\NEVIRAPINE\ZIDOVUDINE
LAMIVUDINE vs LAMIVUDINE\TENOFOVIR
LAMIVUDINE vs LAMIVUDINE\TENOFOVIR DISOPROXIL
LAMIVUDINE vs LAMIVUDINE\ZIDOVUDINE
LAMIVUDINE vs LAMOTRIGINE