Does LAPATINIB Cause Hepatic failure? 19 Reports in FDA Database

Q: Does LAPATINIB cause Hepatic failure?

19 reports of Hepatic failure have been filed with the FDA for LAPATINIB, representing 1.0% of all LAPATINIB adverse event reports.

Q: How dangerous is Hepatic failure from LAPATINIB?

Of 19 reports, 6 (31.6%) resulted in death and 9 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Hepatic failure have been filed in association with LAPATINIB. This represents 1.0% of all adverse event reports for LAPATINIB.

Reports of Hepatic failure with LAPATINIB

1.0%

of all LAPATINIB reports

Deaths

Hospitalizations

How Dangerous Is Hepatic failure From LAPATINIB?

Of the 19 reports, 6 (31.6%) resulted in death, 9 (47.4%) required hospitalization.

Is Hepatic failure Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for LAPATINIB. However, 19 reports have been filed with the FAERS database.

What Other Side Effects Does LAPATINIB Cause?

Diarrhoea (382) Disease progression (227) Palmar-plantar erythrodysaesthesia syndrome (182) Malignant neoplasm progression (173) Nausea (161) Metastases to central nervous system (160) Neutropenia (160) Vomiting (155) Asthenia (148) Fatigue (139)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which LAPATINIB Alternatives Have Lower Hepatic failure Risk?

LAPATINIB vs LAPATINIB DITOSYLATE LAPATINIB vs LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN LAPATINIB vs LARONIDASE LAPATINIB vs LAROTRECTINIB LAPATINIB vs LASILIX

LAPATINIB Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure LAPATINIB Demographics