Does LEFLUNOMIDE Cause Acute hepatic failure? 65 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 65 reports of Acute hepatic failure have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 0.1% of all adverse event reports for LEFLUNOMIDE.
65
Reports of Acute hepatic failure with LEFLUNOMIDE
0.1%
of all LEFLUNOMIDE reports
26
Deaths
41
Hospitalizations
How Dangerous Is Acute hepatic failure From LEFLUNOMIDE?
Of the 65 reports, 26 (40.0%) resulted in death, 41 (63.1%) required hospitalization, and 16 (24.6%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEFLUNOMIDE. However, 65 reports have been filed with the FAERS database.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which LEFLUNOMIDE Alternatives Have Lower Acute hepatic failure Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM