Does LEFLUNOMIDE Cause Duodenal ulcer perforation? 4,200 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 4,200 reports of Duodenal ulcer perforation have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 7.4% of all adverse event reports for LEFLUNOMIDE.
4,200
Reports of Duodenal ulcer perforation with LEFLUNOMIDE
7.4%
of all LEFLUNOMIDE reports
1,824
Deaths
2,314
Hospitalizations
How Dangerous Is Duodenal ulcer perforation From LEFLUNOMIDE?
Of the 4,200 reports, 1,824 (43.4%) resulted in death, 2,314 (55.1%) required hospitalization, and 2,196 (52.3%) were considered life-threatening.
Is Duodenal ulcer perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEFLUNOMIDE. However, 4,200 reports have been filed with the FAERS database.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Duodenal ulcer perforation?
METHOTREXATE (4,239)
FOLIC ACID (4,152)
ABATACEPT (4,147)
TOCILIZUMAB (4,130)
DICLOFENAC (4,120)
CETIRIZINE (4,117)
DESOXIMETASONE (4,084)
RITUXIMAB (4,081)
PREDNISONE (4,060)
ALENDRONATE (4,035)
Which LEFLUNOMIDE Alternatives Have Lower Duodenal ulcer perforation Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM