Does TOCILIZUMAB Cause Duodenal ulcer perforation? 4,130 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 4,130 reports of Duodenal ulcer perforation have been filed in association with TOCILIZUMAB (Tocilizumab-anoh). This represents 4.2% of all adverse event reports for TOCILIZUMAB.
4,130
Reports of Duodenal ulcer perforation with TOCILIZUMAB
4.2%
of all TOCILIZUMAB reports
1,858
Deaths
2,207
Hospitalizations
How Dangerous Is Duodenal ulcer perforation From TOCILIZUMAB?
Of the 4,130 reports, 1,858 (45.0%) resulted in death, 2,207 (53.4%) required hospitalization, and 1,991 (48.2%) were considered life-threatening.
Is Duodenal ulcer perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOCILIZUMAB. However, 4,130 reports have been filed with the FAERS database.
What Other Side Effects Does TOCILIZUMAB Cause?
Drug ineffective (32,342)
Rheumatoid arthritis (20,652)
Pain (18,384)
Off label use (18,256)
Arthralgia (15,536)
Joint swelling (14,831)
Fatigue (13,802)
Rash (12,327)
Drug intolerance (11,952)
Contraindicated product administered (11,547)
What Other Drugs Cause Duodenal ulcer perforation?
METHOTREXATE (4,239)
LEFLUNOMIDE (4,200)
FOLIC ACID (4,152)
ABATACEPT (4,147)
DICLOFENAC (4,120)
CETIRIZINE (4,117)
DESOXIMETASONE (4,084)
RITUXIMAB (4,081)
PREDNISONE (4,060)
ALENDRONATE (4,035)
Which TOCILIZUMAB Alternatives Have Lower Duodenal ulcer perforation Risk?
TOCILIZUMAB vs TOCILIZUMAB-AAZG
TOCILIZUMAB vs TOCOPHEROL
TOCILIZUMAB vs TOFACITINIB
TOCILIZUMAB vs TOFERSEN
TOCILIZUMAB vs TOLNAFTATE