Does RITUXIMAB Cause Duodenal ulcer perforation? 4,081 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 4,081 reports of Duodenal ulcer perforation have been filed in association with RITUXIMAB (Rituxan). This represents 2.3% of all adverse event reports for RITUXIMAB.
4,081
Reports of Duodenal ulcer perforation with RITUXIMAB
2.3%
of all RITUXIMAB reports
1,794
Deaths
2,286
Hospitalizations
How Dangerous Is Duodenal ulcer perforation From RITUXIMAB?
Of the 4,081 reports, 1,794 (44.0%) resulted in death, 2,286 (56.0%) required hospitalization, and 2,053 (50.3%) were considered life-threatening.
Is Duodenal ulcer perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RITUXIMAB. However, 4,081 reports have been filed with the FAERS database.
What Other Side Effects Does RITUXIMAB Cause?
Off label use (39,751)
Drug ineffective (32,186)
Rheumatoid arthritis (19,850)
Pain (16,675)
Fatigue (15,602)
Arthralgia (12,529)
Rash (12,102)
Drug intolerance (11,876)
Infusion related reaction (11,871)
Joint swelling (11,170)
What Other Drugs Cause Duodenal ulcer perforation?
METHOTREXATE (4,239)
LEFLUNOMIDE (4,200)
FOLIC ACID (4,152)
ABATACEPT (4,147)
TOCILIZUMAB (4,130)
DICLOFENAC (4,120)
CETIRIZINE (4,117)
DESOXIMETASONE (4,084)
PREDNISONE (4,060)
ALENDRONATE (4,035)
Which RITUXIMAB Alternatives Have Lower Duodenal ulcer perforation Risk?
RITUXIMAB vs RITUXIMAB-ABBS
RITUXIMAB vs RITUXIMAB-ARRX
RITUXIMAB vs RITUXIMAB-PVVR
RITUXIMAB vs RIVAROXABAN
RITUXIMAB vs RIVASTIGMINE