Does LEFLUNOMIDE Cause Hypertransaminasaemia? 82 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 82 reports of Hypertransaminasaemia have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 0.2% of all adverse event reports for LEFLUNOMIDE.
82
Reports of Hypertransaminasaemia with LEFLUNOMIDE
0.2%
of all LEFLUNOMIDE reports
13
Deaths
26
Hospitalizations
How Dangerous Is Hypertransaminasaemia From LEFLUNOMIDE?
Of the 82 reports, 13 (15.9%) resulted in death, 26 (31.7%) required hospitalization, and 34 (41.5%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEFLUNOMIDE. However, 82 reports have been filed with the FAERS database.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which LEFLUNOMIDE Alternatives Have Lower Hypertransaminasaemia Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM