Does LETROZOLE Cause Hepatic cytolysis? 200 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 200 reports of Hepatic cytolysis have been filed in association with LETROZOLE (Letrozole). This represents 0.6% of all adverse event reports for LETROZOLE.
200
Reports of Hepatic cytolysis with LETROZOLE
0.6%
of all LETROZOLE reports
8
Deaths
103
Hospitalizations
How Dangerous Is Hepatic cytolysis From LETROZOLE?
Of the 200 reports, 8 (4.0%) resulted in death, 103 (51.5%) required hospitalization, and 9 (4.5%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LETROZOLE. However, 200 reports have been filed with the FAERS database.
What Other Side Effects Does LETROZOLE Cause?
Neutropenia (3,683)
Fatigue (3,568)
Malignant neoplasm progression (3,445)
Nausea (2,894)
Arthralgia (2,318)
Diarrhoea (2,282)
Metastases to bone (1,735)
Dyspnoea (1,621)
Asthenia (1,589)
Vomiting (1,560)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which LETROZOLE Alternatives Have Lower Hepatic cytolysis Risk?
LETROZOLE vs LETROZOLE\RIBOCICLIB
LETROZOLE vs LEUCOVORIN
LETROZOLE vs LEUCOVORIN\LEUCOVORIN
LETROZOLE vs LEUPROLIDE
LETROZOLE vs LEVALBUTEROL