Does LETROZOLE Cause Hyperbilirubinaemia? 47 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 47 reports of Hyperbilirubinaemia have been filed in association with LETROZOLE (Letrozole). This represents 0.2% of all adverse event reports for LETROZOLE.
47
Reports of Hyperbilirubinaemia with LETROZOLE
0.2%
of all LETROZOLE reports
18
Deaths
25
Hospitalizations
How Dangerous Is Hyperbilirubinaemia From LETROZOLE?
Of the 47 reports, 18 (38.3%) resulted in death, 25 (53.2%) required hospitalization, and 5 (10.6%) were considered life-threatening.
Is Hyperbilirubinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LETROZOLE. However, 47 reports have been filed with the FAERS database.
What Other Side Effects Does LETROZOLE Cause?
Neutropenia (3,683)
Fatigue (3,568)
Malignant neoplasm progression (3,445)
Nausea (2,894)
Arthralgia (2,318)
Diarrhoea (2,282)
Metastases to bone (1,735)
Dyspnoea (1,621)
Asthenia (1,589)
Vomiting (1,560)
What Other Drugs Cause Hyperbilirubinaemia?
METHOTREXATE (603)
RIBAVIRIN (560)
VINCRISTINE (479)
CYTARABINE (397)
PEGASPARGASE (349)
ACETAMINOPHEN (330)
CYCLOPHOSPHAMIDE (330)
DEXAMETHASONE (315)
CAPECITABINE (279)
SOFOSBUVIR (260)
Which LETROZOLE Alternatives Have Lower Hyperbilirubinaemia Risk?
LETROZOLE vs LETROZOLE\RIBOCICLIB
LETROZOLE vs LEUCOVORIN
LETROZOLE vs LEUCOVORIN\LEUCOVORIN
LETROZOLE vs LEUPROLIDE
LETROZOLE vs LEVALBUTEROL