Does LOPERAMIDE Cause Large intestine perforation? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Large intestine perforation have been filed in association with LOPERAMIDE (Anti-diarrheal). This represents 0.1% of all adverse event reports for LOPERAMIDE.
14
Reports of Large intestine perforation with LOPERAMIDE
0.1%
of all LOPERAMIDE reports
6
Deaths
9
Hospitalizations
How Dangerous Is Large intestine perforation From LOPERAMIDE?
Of the 14 reports, 6 (42.9%) resulted in death, 9 (64.3%) required hospitalization, and 5 (35.7%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LOPERAMIDE. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does LOPERAMIDE Cause?
Drug ineffective (3,207)
Diarrhoea (1,909)
Constipation (1,614)
Off label use (1,378)
Incorrect dose administered (1,178)
Drug abuse (1,088)
Nausea (997)
Intentional product use issue (871)
Overdose (857)
Toxicity to various agents (753)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which LOPERAMIDE Alternatives Have Lower Large intestine perforation Risk?
LOPERAMIDE vs LOPINAVIR
LOPERAMIDE vs LOPINAVIR\RITONAVIR
LOPERAMIDE vs LOPRAZOLAM
LOPERAMIDE vs LORATADINE
LOPERAMIDE vs LORATADINE\PSEUDOEPHEDRINE