Does LOPINAVIR Cause Splenomegaly? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Splenomegaly have been filed in association with LOPINAVIR (Kaletra). This represents 0.4% of all adverse event reports for LOPINAVIR.
5
Reports of Splenomegaly with LOPINAVIR
0.4%
of all LOPINAVIR reports
2
Deaths
1
Hospitalizations
How Dangerous Is Splenomegaly From LOPINAVIR?
Of the 5 reports, 2 (40.0%) resulted in death, 1 (20.0%) required hospitalization.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LOPINAVIR. However, 5 reports have been filed with the FAERS database.
What Other Side Effects Does LOPINAVIR Cause?
Foetal exposure during pregnancy (244)
Exposure during pregnancy (184)
Virologic failure (170)
Drug resistance (134)
Off label use (133)
Lipodystrophy acquired (126)
Premature baby (107)
Diplopia (89)
Treatment failure (89)
Premature delivery (88)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which LOPINAVIR Alternatives Have Lower Splenomegaly Risk?
LOPINAVIR vs LOPINAVIR\RITONAVIR
LOPINAVIR vs LOPRAZOLAM
LOPINAVIR vs LORATADINE
LOPINAVIR vs LORATADINE\PSEUDOEPHEDRINE
LOPINAVIR vs LORAZEPAM