Does LOPINAVIR\RITONAVIR Cause Hypertransaminasaemia? 92 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 92 reports of Hypertransaminasaemia have been filed in association with LOPINAVIR\RITONAVIR. This represents 1.1% of all adverse event reports for LOPINAVIR\RITONAVIR.
92
Reports of Hypertransaminasaemia with LOPINAVIR\RITONAVIR
1.1%
of all LOPINAVIR\RITONAVIR reports
26
Deaths
15
Hospitalizations
How Dangerous Is Hypertransaminasaemia From LOPINAVIR\RITONAVIR?
Of the 92 reports, 26 (28.3%) resulted in death, 15 (16.3%) required hospitalization, and 15 (16.3%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LOPINAVIR\RITONAVIR. However, 92 reports have been filed with the FAERS database.
What Other Side Effects Does LOPINAVIR\RITONAVIR Cause?
Off label use (2,010)
Foetal exposure during pregnancy (932)
Drug interaction (821)
Depression (551)
Virologic failure (428)
Exposure during pregnancy (395)
Diarrhoea (363)
Maternal exposure during pregnancy (311)
Product use in unapproved indication (282)
Nausea (243)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which LOPINAVIR\RITONAVIR Alternatives Have Lower Hypertransaminasaemia Risk?
LOPINAVIR\RITONAVIR vs LOPRAZOLAM
LOPINAVIR\RITONAVIR vs LORATADINE
LOPINAVIR\RITONAVIR vs LORATADINE\PSEUDOEPHEDRINE
LOPINAVIR\RITONAVIR vs LORAZEPAM
LOPINAVIR\RITONAVIR vs LORCASERIN