Does LORLATINIB Cause Hypertransaminasaemia? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Hypertransaminasaemia have been filed in association with LORLATINIB (Lorbrena). This represents 0.1% of all adverse event reports for LORLATINIB.
6
Reports of Hypertransaminasaemia with LORLATINIB
0.1%
of all LORLATINIB reports
0
Deaths
2
Hospitalizations
How Dangerous Is Hypertransaminasaemia From LORLATINIB?
Of the 6 reports, 2 (33.3%) required hospitalization.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LORLATINIB. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does LORLATINIB Cause?
Death (1,050)
Neoplasm progression (633)
Off label use (394)
Weight increased (306)
Hallucination (290)
Blood cholesterol increased (281)
Dyspnoea (223)
Oedema peripheral (198)
Oedema (195)
Fatigue (188)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which LORLATINIB Alternatives Have Lower Hypertransaminasaemia Risk?
LORLATINIB vs LORMETAZEPAM
LORLATINIB vs LORNOXICAM
LORLATINIB vs LOSARTAN
LORLATINIB vs LOSARTAN\LOSARTAN
LORLATINIB vs LOTEPREDNOL ETABONATE