Does MELPHALAN Cause Adrenal insufficiency? 29 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 29 reports of Adrenal insufficiency have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 0.2% of all adverse event reports for MELPHALAN.
29
Reports of Adrenal insufficiency with MELPHALAN
0.2%
of all MELPHALAN reports
7
Deaths
12
Hospitalizations
How Dangerous Is Adrenal insufficiency From MELPHALAN?
Of the 29 reports, 7 (24.1%) resulted in death, 12 (41.4%) required hospitalization, and 4 (13.8%) were considered life-threatening.
Is Adrenal insufficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 29 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Adrenal insufficiency?
NIVOLUMAB (1,285)
PEMBROLIZUMAB (1,270)
PREDNISONE (1,105)
IPILIMUMAB (851)
METHOTREXATE (644)
ADALIMUMAB (554)
ETANERCEPT (546)
TOCILIZUMAB (541)
HYDROXYCHLOROQUINE (517)
INFLIXIMAB (509)
Which MELPHALAN Alternatives Have Lower Adrenal insufficiency Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL