Does MELPHALAN Cause Bone marrow failure? 163 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 163 reports of Bone marrow failure have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 1.0% of all adverse event reports for MELPHALAN.
163
Reports of Bone marrow failure with MELPHALAN
1.0%
of all MELPHALAN reports
47
Deaths
67
Hospitalizations
How Dangerous Is Bone marrow failure From MELPHALAN?
Of the 163 reports, 47 (28.8%) resulted in death, 67 (41.1%) required hospitalization, and 35 (21.5%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 163 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which MELPHALAN Alternatives Have Lower Bone marrow failure Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL