Does MELPHALAN Cause Haematotoxicity? 133 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 133 reports of Haematotoxicity have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 0.8% of all adverse event reports for MELPHALAN.
133
Reports of Haematotoxicity with MELPHALAN
0.8%
of all MELPHALAN reports
15
Deaths
14
Hospitalizations
How Dangerous Is Haematotoxicity From MELPHALAN?
Of the 133 reports, 15 (11.3%) resulted in death, 14 (10.5%) required hospitalization, and 8 (6.0%) were considered life-threatening.
Is Haematotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 133 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Haematotoxicity?
CYCLOPHOSPHAMIDE (1,410)
DOXORUBICIN (1,180)
VINCRISTINE (1,038)
RITUXIMAB (812)
CARBOPLATIN (803)
METHOTREXATE (799)
PREDNISONE (730)
CYTARABINE (701)
ETOPOSIDE (677)
CISPLATIN (668)
Which MELPHALAN Alternatives Have Lower Haematotoxicity Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL