Does MELPHALAN Cause Progressive multifocal leukoencephalopathy? 150 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 150 reports of Progressive multifocal leukoencephalopathy have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 0.9% of all adverse event reports for MELPHALAN.
150
Reports of Progressive multifocal leukoencephalopathy with MELPHALAN
0.9%
of all MELPHALAN reports
74
Deaths
60
Hospitalizations
How Dangerous Is Progressive multifocal leukoencephalopathy From MELPHALAN?
Of the 150 reports, 74 (49.3%) resulted in death, 60 (40.0%) required hospitalization, and 27 (18.0%) were considered life-threatening.
Is Progressive multifocal leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 150 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Progressive multifocal leukoencephalopathy?
NATALIZUMAB (1,668)
RITUXIMAB (1,647)
CYCLOPHOSPHAMIDE (782)
PREDNISONE (606)
PREDNISOLONE (439)
TACROLIMUS (438)
METHOTREXATE (428)
DOXORUBICIN (421)
MYCOPHENOLATE MOFETIL (414)
VINCRISTINE (376)
Which MELPHALAN Alternatives Have Lower Progressive multifocal leukoencephalopathy Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL