Does MERCAPTOPURINE Cause Hypertransaminasaemia? 60 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 60 reports of Hypertransaminasaemia have been filed in association with MERCAPTOPURINE (Mercaptopurine). This represents 0.5% of all adverse event reports for MERCAPTOPURINE.
60
Reports of Hypertransaminasaemia with MERCAPTOPURINE
0.5%
of all MERCAPTOPURINE reports
0
Deaths
42
Hospitalizations
How Dangerous Is Hypertransaminasaemia From MERCAPTOPURINE?
Of the 60 reports, 42 (70.0%) required hospitalization, and 6 (10.0%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MERCAPTOPURINE. However, 60 reports have been filed with the FAERS database.
What Other Side Effects Does MERCAPTOPURINE Cause?
Febrile neutropenia (1,853)
Off label use (893)
Pyrexia (855)
Drug ineffective (721)
Vomiting (488)
Neutropenia (485)
Nausea (418)
Pneumonia (394)
Pancytopenia (392)
Sepsis (389)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which MERCAPTOPURINE Alternatives Have Lower Hypertransaminasaemia Risk?
MERCAPTOPURINE vs MEROPENEM
MERCAPTOPURINE vs MEROPENEM ANHYDROUS
MERCAPTOPURINE vs MESALAMINE
MERCAPTOPURINE vs MESNA
MERCAPTOPURINE vs METAMIZOLE