MESNA for Infection prophylaxis: Side Effects & Safety Data
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There are 204 adverse event reports in the FDA FAERS database where MESNA was used for Infection prophylaxis.
Most Reported Side Effects for MESNA
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 707 | 14.5% | 47 | 532 |
| Pyrexia | 352 | 7.2% | 46 | 249 |
| Off label use | 299 | 6.1% | 51 | 138 |
| Cystitis haemorrhagic | 294 | 6.0% | 9 | 23 |
| Disease progression | 273 | 5.6% | 151 | 9 |
| Neutropenia | 238 | 4.9% | 36 | 96 |
| Encephalopathy | 226 | 4.6% | 27 | 148 |
| Vomiting | 200 | 4.1% | 36 | 120 |
| Death | 184 | 3.8% | 184 | 13 |
| Pancytopenia | 179 | 3.7% | 20 | 96 |
| Diarrhoea | 177 | 3.6% | 35 | 110 |
| Sepsis | 173 | 3.5% | 77 | 80 |
| Bacterial infection | 172 | 3.5% | 151 | 23 |
| Nausea | 166 | 3.4% | 20 | 81 |
| Anaemia | 163 | 3.3% | 16 | 89 |
Other Indications for MESNA
Prophylaxis (566)
Product used for unknown indication (554)
Acute lymphocytic leukaemia (502)
Diffuse large b-cell lymphoma (200)
Non-hodgkin's lymphoma (113)
B-cell lymphoma (91)
Burkitt's lymphoma (88)
Ewing's sarcoma (88)
Neuroblastoma (85)
Chemotherapy (71)
Other Drugs Used for Infection prophylaxis
SULFAMETHOXAZOLE\TRIMETHOPRIM (1,215)
VALACYCLOVIR (704)
CHLORHEXIDINE\ISOPROPYL ALCOHOL (670)
ACYCLOVIR (317)
LEVOFLOXACIN (273)
CHLORHEXIDINE (248)
CIPROFLOXACIN (218)
ALCOHOL (202)
FLUCONAZOLE (194)
POSACONAZOLE (170)