Does MESNA Cause Sepsis? 173 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 173 reports of Sepsis have been filed in association with MESNA (mesna). This represents 3.5% of all adverse event reports for MESNA.
173
Reports of Sepsis with MESNA
3.5%
of all MESNA reports
77
Deaths
80
Hospitalizations
How Dangerous Is Sepsis From MESNA?
Of the 173 reports, 77 (44.5%) resulted in death, 80 (46.2%) required hospitalization, and 37 (21.4%) were considered life-threatening.
Is Sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 173 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
What Other Drugs Cause Sepsis?
RITUXIMAB (4,043)
CYCLOPHOSPHAMIDE (4,041)
METHOTREXATE (3,933)
ADALIMUMAB (3,169)
DEXAMETHASONE (3,150)
LENALIDOMIDE (2,956)
VINCRISTINE (2,791)
DOXORUBICIN (2,740)
PREDNISONE (2,634)
PREDNISOLONE (2,281)
Which MESNA Alternatives Have Lower Sepsis Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE