Does MESNA Cause Hyperthermia? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Hyperthermia have been filed in association with MESNA (mesna). This represents 0.3% of all adverse event reports for MESNA.
15
Reports of Hyperthermia with MESNA
0.3%
of all MESNA reports
2
Deaths
10
Hospitalizations
How Dangerous Is Hyperthermia From MESNA?
Of the 15 reports, 2 (13.3%) resulted in death, 10 (66.7%) required hospitalization, and 1 (6.7%) were considered life-threatening.
Is Hyperthermia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
What Other Drugs Cause Hyperthermia?
QUETIAPINE (265)
OLANZAPINE (210)
ACETAMINOPHEN (196)
OXALIPLATIN (195)
RISPERIDONE (166)
LAMOTRIGINE (156)
HALOPERIDOL (138)
CARBOPLATIN (129)
FLUOROURACIL (115)
SERTRALINE (109)
Which MESNA Alternatives Have Lower Hyperthermia Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE