Does MESNA Cause Thymus hypoplasia? 48 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 48 reports of Thymus hypoplasia have been filed in association with MESNA (mesna). This represents 1.0% of all adverse event reports for MESNA.
48
Reports of Thymus hypoplasia with MESNA
1.0%
of all MESNA reports
48
Deaths
6
Hospitalizations
How Dangerous Is Thymus hypoplasia From MESNA?
Of the 48 reports, 48 (100.0%) resulted in death, 6 (12.5%) required hospitalization.
Is Thymus hypoplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 48 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
What Other Drugs Cause Thymus hypoplasia?
CYCLOPHOSPHAMIDE (148)
CYTARABINE (148)
DAUNORUBICIN (148)
DEXAMETHASONE (148)
ETOPOSIDE (148)
FILGRASTIM (144)
CYCLOSPORINE (111)
MERCAPTOPURINE (84)
METHOTREXATE (84)
METHYLPREDNISOLONE (84)
Which MESNA Alternatives Have Lower Thymus hypoplasia Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE