Does MITOXANTRONE Cause Hepatic cytolysis? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Hepatic cytolysis have been filed in association with MITOXANTRONE (mitoXANTRONE). This represents 0.3% of all adverse event reports for MITOXANTRONE.
11
Reports of Hepatic cytolysis with MITOXANTRONE
0.3%
of all MITOXANTRONE reports
1
Deaths
3
Hospitalizations
How Dangerous Is Hepatic cytolysis From MITOXANTRONE?
Of the 11 reports, 1 (9.1%) resulted in death, 3 (27.3%) required hospitalization, and 3 (27.3%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MITOXANTRONE. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does MITOXANTRONE Cause?
Febrile neutropenia (668)
Off label use (368)
Neutropenia (296)
Drug ineffective (293)
Thrombocytopenia (256)
Sepsis (240)
Pyrexia (214)
Product use in unapproved indication (177)
Disease progression (173)
Acute myeloid leukaemia (167)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which MITOXANTRONE Alternatives Have Lower Hepatic cytolysis Risk?
MITOXANTRONE vs MITRAGYNINE\HERBALS
MITOXANTRONE vs MIZORIBINE
MITOXANTRONE vs MOBOCERTINIB
MITOXANTRONE vs MOCLOBEMIDE
MITOXANTRONE vs MODAFINIL