Does NAVITOCLAX Cause Splenomegaly? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Splenomegaly have been filed in association with NAVITOCLAX. This represents 2.9% of all adverse event reports for NAVITOCLAX.
5
Reports of Splenomegaly with NAVITOCLAX
2.9%
of all NAVITOCLAX reports
2
Deaths
1
Hospitalizations
How Dangerous Is Splenomegaly From NAVITOCLAX?
Of the 5 reports, 2 (40.0%) resulted in death, 1 (20.0%) required hospitalization, and 1 (20.0%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NAVITOCLAX. However, 5 reports have been filed with the FAERS database.
What Other Side Effects Does NAVITOCLAX Cause?
Sepsis (25)
Pneumonia (24)
Thrombocytopenia (21)
Febrile neutropenia (17)
Pyrexia (16)
Fatigue (14)
Anaemia (13)
Diarrhoea (13)
Acute kidney injury (12)
Off label use (11)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which NAVITOCLAX Alternatives Have Lower Splenomegaly Risk?
NAVITOCLAX vs NAXITAMAB-GQGK
NAVITOCLAX vs NEBIVOLOL
NAVITOCLAX vs NECITUMUMAB
NAVITOCLAX vs NEDAPLATIN
NAVITOCLAX vs NEFAZODONE