Does NIRAPARIB Cause Hepatic failure? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Hepatic failure have been filed in association with NIRAPARIB (ZEJULA). This represents 0.1% of all adverse event reports for NIRAPARIB.
13
Reports of Hepatic failure with NIRAPARIB
0.1%
of all NIRAPARIB reports
1
Deaths
7
Hospitalizations
How Dangerous Is Hepatic failure From NIRAPARIB?
Of the 13 reports, 1 (7.7%) resulted in death, 7 (53.8%) required hospitalization, and 2 (15.4%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIRAPARIB. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does NIRAPARIB Cause?
Nausea (5,794)
Fatigue (5,240)
Constipation (4,128)
Platelet count decreased (4,102)
Insomnia (2,861)
Blood pressure increased (2,464)
Headache (2,383)
Off label use (2,213)
Vomiting (2,029)
Carbohydrate antigen 125 increased (1,868)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which NIRAPARIB Alternatives Have Lower Hepatic failure Risk?
NIRAPARIB vs NIRMATRELVIR\RITONAVIR
NIRAPARIB vs NIROGACESTAT
NIRAPARIB vs NIROGACESTAT HYDROBROMIDE
NIRAPARIB vs NIRSEVIMAB
NIRAPARIB vs NIRSEVIMAB-ALIP