Does NITISINONE Cause Acute hepatic failure? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Acute hepatic failure have been filed in association with NITISINONE (Nitisinone). This represents 0.8% of all adverse event reports for NITISINONE.
6
Reports of Acute hepatic failure with NITISINONE
0.8%
of all NITISINONE reports
3
Deaths
2
Hospitalizations
How Dangerous Is Acute hepatic failure From NITISINONE?
Of the 6 reports, 3 (50.0%) resulted in death, 2 (33.3%) required hospitalization, and 1 (16.7%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NITISINONE. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does NITISINONE Cause?
Amino acid level increased (118)
Liver transplant (62)
Hepatocellular carcinoma (58)
Cataract (47)
Off label use (41)
Alpha 1 foetoprotein increased (39)
Lenticular opacities (34)
Vomiting (32)
Succinylacetone increased (31)
Treatment noncompliance (30)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which NITISINONE Alternatives Have Lower Acute hepatic failure Risk?
NITISINONE vs NITRAZEPAM
NITISINONE vs NITRENDIPINE
NITISINONE vs NITRIC
NITISINONE vs NITROFURANTOIN
NITISINONE vs NITROFURANTOIN\NITROFURANTOIN