Does PACLITAXEL Cause Hypernatraemia? 39 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 39 reports of Hypernatraemia have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.1% of all adverse event reports for PACLITAXEL.
39
Reports of Hypernatraemia with PACLITAXEL
0.1%
of all PACLITAXEL reports
26
Deaths
32
Hospitalizations
How Dangerous Is Hypernatraemia From PACLITAXEL?
Of the 39 reports, 26 (66.7%) resulted in death, 32 (82.1%) required hospitalization, and 5 (12.8%) were considered life-threatening.
Is Hypernatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 39 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Hypernatraemia?
TOLVAPTAN (235)
FUROSEMIDE (192)
LITHIUM (186)
SODIUM (136)
LAMOTRIGINE (90)
VALPROIC ACID (88)
OLANZAPINE (87)
METFORMIN (79)
QUETIAPINE (77)
ARIPIPRAZOLE (69)
Which PACLITAXEL Alternatives Have Lower Hypernatraemia Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON