Does PEGASPARGASE Cause Acidosis? 32 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 32 reports of Acidosis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.3% of all adverse event reports for PEGASPARGASE.
32
Reports of Acidosis with PEGASPARGASE
0.3%
of all PEGASPARGASE reports
24
Deaths
28
Hospitalizations
How Dangerous Is Acidosis From PEGASPARGASE?
Of the 32 reports, 24 (75.0%) resulted in death, 28 (87.5%) required hospitalization, and 4 (12.5%) were considered life-threatening.
Is Acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 32 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Acidosis?
METFORMIN (427)
ACETAMINOPHEN (313)
EMPAGLIFLOZIN (179)
IBUPROFEN (162)
AMLODIPINE (133)
TRAMADOL (116)
TACROLIMUS (114)
MORPHINE (100)
QUETIAPINE (99)
PREDNISONE (94)
Which PEGASPARGASE Alternatives Have Lower Acidosis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ