Does PEGASPARGASE Cause Ascites? 139 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 139 reports of Ascites have been filed in association with PEGASPARGASE (ONCASPAR). This represents 1.2% of all adverse event reports for PEGASPARGASE.
139
Reports of Ascites with PEGASPARGASE
1.2%
of all PEGASPARGASE reports
37
Deaths
105
Hospitalizations
How Dangerous Is Ascites From PEGASPARGASE?
Of the 139 reports, 37 (26.6%) resulted in death, 105 (75.5%) required hospitalization, and 11 (7.9%) were considered life-threatening.
Is Ascites Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 139 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Ascites?
BEVACIZUMAB (1,067)
RIBAVIRIN (1,025)
TREPROSTINIL (672)
ACETAMINOPHEN (599)
SOFOSBUVIR (598)
PACLITAXEL (581)
LETROZOLE (579)
CYCLOPHOSPHAMIDE (561)
OXALIPLATIN (533)
METHOTREXATE (521)
Which PEGASPARGASE Alternatives Have Lower Ascites Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ