Does PEGASPARGASE Cause Aspergillus infection? 172 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 172 reports of Aspergillus infection have been filed in association with PEGASPARGASE (ONCASPAR). This represents 1.5% of all adverse event reports for PEGASPARGASE.
172
Reports of Aspergillus infection with PEGASPARGASE
1.5%
of all PEGASPARGASE reports
110
Deaths
63
Hospitalizations
How Dangerous Is Aspergillus infection From PEGASPARGASE?
Of the 172 reports, 110 (64.0%) resulted in death, 63 (36.6%) required hospitalization, and 31 (18.0%) were considered life-threatening.
Is Aspergillus infection Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 172 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Aspergillus infection?
PREDNISONE (1,231)
TACROLIMUS (1,099)
RITUXIMAB (952)
MYCOPHENOLATE MOFETIL (888)
METHOTREXATE (828)
METHYLPREDNISOLONE (788)
DEXAMETHASONE (785)
CYCLOPHOSPHAMIDE (733)
ETOPOSIDE (676)
PREDNISOLONE (667)
Which PEGASPARGASE Alternatives Have Lower Aspergillus infection Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ