Does PEGASPARGASE Cause Bradycardia? 98 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 98 reports of Bradycardia have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.9% of all adverse event reports for PEGASPARGASE.
98
Reports of Bradycardia with PEGASPARGASE
0.9%
of all PEGASPARGASE reports
51
Deaths
57
Hospitalizations
How Dangerous Is Bradycardia From PEGASPARGASE?
Of the 98 reports, 51 (52.0%) resulted in death, 57 (58.2%) required hospitalization, and 8 (8.2%) were considered life-threatening.
Is Bradycardia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 98 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Bradycardia?
BISOPROLOL (2,535)
METOPROLOL (2,024)
AMLODIPINE (1,840)
AMIODARONE (1,261)
FUROSEMIDE (1,032)
ATENOLOL (942)
PROPRANOLOL (934)
DIGOXIN (896)
CARVEDILOL (861)
FINGOLIMOD (861)
Which PEGASPARGASE Alternatives Have Lower Bradycardia Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ