Does PEGASPARGASE Cause Colitis? 200 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 200 reports of Colitis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 1.7% of all adverse event reports for PEGASPARGASE.
200
Reports of Colitis with PEGASPARGASE
1.7%
of all PEGASPARGASE reports
46
Deaths
178
Hospitalizations
How Dangerous Is Colitis From PEGASPARGASE?
Of the 200 reports, 46 (23.0%) resulted in death, 178 (89.0%) required hospitalization, and 18 (9.0%) were considered life-threatening.
Is Colitis Listed in the Official Label?
Yes, Colitis is listed as a known adverse reaction in the official FDA drug label for PEGASPARGASE.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Colitis?
ADALIMUMAB (3,043)
NIVOLUMAB (2,123)
IPILIMUMAB (1,988)
PEMBROLIZUMAB (1,638)
INFLIXIMAB (1,254)
METHOTREXATE (1,166)
PREDNISONE (1,100)
VEDOLIZUMAB (1,077)
CARBOPLATIN (993)
MESALAMINE (839)
Which PEGASPARGASE Alternatives Have Lower Colitis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ