Does PEGASPARGASE Cause Endophthalmitis? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Endophthalmitis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.2% of all adverse event reports for PEGASPARGASE.
19
Reports of Endophthalmitis with PEGASPARGASE
0.2%
of all PEGASPARGASE reports
4
Deaths
17
Hospitalizations
How Dangerous Is Endophthalmitis From PEGASPARGASE?
Of the 19 reports, 4 (21.1%) resulted in death, 17 (89.5%) required hospitalization, and 4 (21.1%) were considered life-threatening.
Is Endophthalmitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 19 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Endophthalmitis?
AFLIBERCEPT (1,289)
BEVACIZUMAB (903)
RANIBIZUMAB (542)
DEXAMETHASONE (439)
PREDNISOLONE (217)
TACROLIMUS (200)
PREDNISONE (192)
CALCIUM\MAGNESIUM\POTASSIUM\SODIUM\SODIUM\SODIUM (186)
MOXIFLOXACIN (175)
MYCOPHENOLATE MOFETIL (162)
Which PEGASPARGASE Alternatives Have Lower Endophthalmitis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ