Does PEGASPARGASE Cause Enterocolitis? 44 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 44 reports of Enterocolitis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.4% of all adverse event reports for PEGASPARGASE.
44
Reports of Enterocolitis with PEGASPARGASE
0.4%
of all PEGASPARGASE reports
9
Deaths
40
Hospitalizations
How Dangerous Is Enterocolitis From PEGASPARGASE?
Of the 44 reports, 9 (20.5%) resulted in death, 40 (90.9%) required hospitalization, and 12 (27.3%) were considered life-threatening.
Is Enterocolitis Listed in the Official Label?
Yes, Enterocolitis is listed as a known adverse reaction in the official FDA drug label for PEGASPARGASE.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Enterocolitis?
NIVOLUMAB (471)
IPILIMUMAB (321)
CAPECITABINE (291)
OXALIPLATIN (227)
METHOTREXATE (191)
PEMBROLIZUMAB (180)
RITUXIMAB (174)
DEXAMETHASONE (162)
BEVACIZUMAB (161)
CARBOPLATIN (160)
Which PEGASPARGASE Alternatives Have Lower Enterocolitis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ