Does PEGASPARGASE Cause Haemolysis? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Haemolysis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.1% of all adverse event reports for PEGASPARGASE.
8
Reports of Haemolysis with PEGASPARGASE
0.1%
of all PEGASPARGASE reports
3
Deaths
4
Hospitalizations
How Dangerous Is Haemolysis From PEGASPARGASE?
Of the 8 reports, 3 (37.5%) resulted in death, 4 (50.0%) required hospitalization, and 1 (12.5%) were considered life-threatening.
Is Haemolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 8 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Haemolysis?
ECULIZUMAB (1,476)
HUMAN IMMUNOGLOBULIN G (357)
RITUXIMAB (261)
RAVULIZUMAB-CWVZ (242)
PREDNISONE (192)
CYCLOSPORINE (173)
DEXAMETHASONE (167)
ACETAMINOPHEN (134)
VINCRISTINE (132)
TACROLIMUS (116)
Which PEGASPARGASE Alternatives Have Lower Haemolysis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ