Does PEGASPARGASE Cause Herpes simplex? 57 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 57 reports of Herpes simplex have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.5% of all adverse event reports for PEGASPARGASE.
57
Reports of Herpes simplex with PEGASPARGASE
0.5%
of all PEGASPARGASE reports
34
Deaths
24
Hospitalizations
How Dangerous Is Herpes simplex From PEGASPARGASE?
Of the 57 reports, 34 (59.6%) resulted in death, 24 (42.1%) required hospitalization, and 2 (3.5%) were considered life-threatening.
Is Herpes simplex Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 57 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Herpes simplex?
PREDNISONE (445)
CYCLOPHOSPHAMIDE (395)
METHOTREXATE (395)
MYCOPHENOLATE MOFETIL (353)
TACROLIMUS (328)
RITUXIMAB (309)
PREDNISOLONE (296)
VINCRISTINE (242)
FLUDARABINE (218)
METHYLPREDNISOLONE (218)
Which PEGASPARGASE Alternatives Have Lower Herpes simplex Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ