Does PEGASPARGASE Cause Hypercapnia? 7 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7 reports of Hypercapnia have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.1% of all adverse event reports for PEGASPARGASE.
7
Reports of Hypercapnia with PEGASPARGASE
0.1%
of all PEGASPARGASE reports
6
Deaths
6
Hospitalizations
How Dangerous Is Hypercapnia From PEGASPARGASE?
Of the 7 reports, 6 (85.7%) resulted in death, 6 (85.7%) required hospitalization, and 3 (42.9%) were considered life-threatening.
Is Hypercapnia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 7 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Hypercapnia?
ALBUTEROL (105)
MORPHINE (85)
PREDNISONE (69)
QUETIAPINE (67)
PREDNISOLONE (66)
MEPOLIZUMAB (62)
PREGABALIN (60)
METHYLPREDNISOLONE (56)
HYDROCORTISONE (55)
MACITENTAN (55)
Which PEGASPARGASE Alternatives Have Lower Hypercapnia Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ