Does PEGASPARGASE Cause Intestinal ischaemia? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Intestinal ischaemia have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.1% of all adverse event reports for PEGASPARGASE.
15
Reports of Intestinal ischaemia with PEGASPARGASE
0.1%
of all PEGASPARGASE reports
10
Deaths
10
Hospitalizations
How Dangerous Is Intestinal ischaemia From PEGASPARGASE?
Of the 15 reports, 10 (66.7%) resulted in death, 10 (66.7%) required hospitalization, and 4 (26.7%) were considered life-threatening.
Is Intestinal ischaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Intestinal ischaemia?
PROPOFOL (128)
FLUOROURACIL (119)
OXALIPLATIN (119)
METHYLPREDNISOLONE (109)
CLOZAPINE (93)
DOCETAXEL (89)
AMLODIPINE (87)
METHOTREXATE (87)
PREDNISONE (83)
MIDAZOLAM (81)
Which PEGASPARGASE Alternatives Have Lower Intestinal ischaemia Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ