Does PEGASPARGASE Cause Leukopenia? 115 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 115 reports of Leukopenia have been filed in association with PEGASPARGASE (ONCASPAR). This represents 1.0% of all adverse event reports for PEGASPARGASE.
115
Reports of Leukopenia with PEGASPARGASE
1.0%
of all PEGASPARGASE reports
18
Deaths
69
Hospitalizations
How Dangerous Is Leukopenia From PEGASPARGASE?
Of the 115 reports, 18 (15.7%) resulted in death, 69 (60.0%) required hospitalization, and 15 (13.0%) were considered life-threatening.
Is Leukopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 115 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which PEGASPARGASE Alternatives Have Lower Leukopenia Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ