Does PEGASPARGASE Cause Pneumonitis? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Pneumonitis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.2% of all adverse event reports for PEGASPARGASE.
20
Reports of Pneumonitis with PEGASPARGASE
0.2%
of all PEGASPARGASE reports
3
Deaths
16
Hospitalizations
How Dangerous Is Pneumonitis From PEGASPARGASE?
Of the 20 reports, 3 (15.0%) resulted in death, 16 (80.0%) required hospitalization, and 1 (5.0%) were considered life-threatening.
Is Pneumonitis Listed in the Official Label?
Yes, Pneumonitis is listed as a known adverse reaction in the official FDA drug label for PEGASPARGASE.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Pneumonitis?
NIVOLUMAB (2,076)
PEMBROLIZUMAB (1,933)
METHOTREXATE (1,188)
PACLITAXEL (1,110)
CARBOPLATIN (975)
EVEROLIMUS (919)
IPILIMUMAB (891)
ATEZOLIZUMAB (842)
DURVALUMAB (827)
RITUXIMAB (747)
Which PEGASPARGASE Alternatives Have Lower Pneumonitis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ