Does PEGASPARGASE Cause Tracheitis? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Tracheitis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.1% of all adverse event reports for PEGASPARGASE.
12
Reports of Tracheitis with PEGASPARGASE
0.1%
of all PEGASPARGASE reports
12
Deaths
11
Hospitalizations
How Dangerous Is Tracheitis From PEGASPARGASE?
Of the 12 reports, 12 (100.0%) resulted in death, 11 (91.7%) required hospitalization, and 10 (83.3%) were considered life-threatening.
Is Tracheitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Tracheitis?
PREDNISONE (30)
MYCOPHENOLATE MOFETIL (27)
METHOTREXATE (25)
BOSENTAN (21)
CYCLOPHOSPHAMIDE (21)
PALIVIZUMAB (19)
HUMAN IMMUNOGLOBULIN G (18)
METHYLPREDNISOLONE (18)
TACROLIMUS (18)
PREDNISOLONE (17)
Which PEGASPARGASE Alternatives Have Lower Tracheitis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ