Does PEGINTERFERON ALFA-2B Cause Hepatic failure? 49 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 49 reports of Hepatic failure have been filed in association with PEGINTERFERON ALFA-2B. This represents 1.2% of all adverse event reports for PEGINTERFERON ALFA-2B.
49
Reports of Hepatic failure with PEGINTERFERON ALFA-2B
1.2%
of all PEGINTERFERON ALFA-2B reports
23
Deaths
15
Hospitalizations
How Dangerous Is Hepatic failure From PEGINTERFERON ALFA-2B?
Of the 49 reports, 23 (46.9%) resulted in death, 15 (30.6%) required hospitalization, and 3 (6.1%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGINTERFERON ALFA-2B. However, 49 reports have been filed with the FAERS database.
What Other Side Effects Does PEGINTERFERON ALFA-2B Cause?
Anaemia (804)
Platelet count decreased (593)
Pyrexia (440)
White blood cell count decreased (420)
Haemoglobin decreased (281)
Neutrophil count decreased (272)
Nausea (269)
Rash (269)
Fatigue (245)
Decreased appetite (224)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which PEGINTERFERON ALFA-2B Alternatives Have Lower Hepatic failure Risk?
PEGINTERFERON ALFA-2B vs PEGINTERFERON BETA-1A
PEGINTERFERON ALFA-2B vs PEGINTRON
PEGINTERFERON ALFA-2B vs PEGLOTICASE
PEGINTERFERON ALFA-2B vs PEGUNIGALSIDASE ALFA-IWXJ
PEGINTERFERON ALFA-2B vs PEGVALIASE-PQPZ