Does PEMBROLIZUMAB Cause Acute hepatic failure? 57 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 57 reports of Acute hepatic failure have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
57
Reports of Acute hepatic failure with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
37
Deaths
32
Hospitalizations
How Dangerous Is Acute hepatic failure From PEMBROLIZUMAB?
Of the 57 reports, 37 (64.9%) resulted in death, 32 (56.1%) required hospitalization, and 13 (22.8%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 57 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which PEMBROLIZUMAB Alternatives Have Lower Acute hepatic failure Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G