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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does PEMBROLIZUMAB Cause Hyperbilirubinaemia? 86 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 86 reports of Hyperbilirubinaemia have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.

86
Reports of Hyperbilirubinaemia with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
14
Deaths
43
Hospitalizations

How Dangerous Is Hyperbilirubinaemia From PEMBROLIZUMAB?

Of the 86 reports, 14 (16.3%) resulted in death, 43 (50.0%) required hospitalization, and 9 (10.5%) were considered life-threatening.

Is Hyperbilirubinaemia Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 86 reports have been filed with the FAERS database.

What Other Side Effects Does PEMBROLIZUMAB Cause?

Malignant neoplasm progression (10,111) Death (4,744) Diarrhoea (4,251) Fatigue (3,833) Off label use (3,416) Product use in unapproved indication (3,191) Pyrexia (3,155) Rash (2,900) Nausea (2,670) Decreased appetite (2,486)

What Other Drugs Cause Hyperbilirubinaemia?

METHOTREXATE (603) RIBAVIRIN (560) VINCRISTINE (479) CYTARABINE (397) PEGASPARGASE (349) ACETAMINOPHEN (330) CYCLOPHOSPHAMIDE (330) DEXAMETHASONE (315) CAPECITABINE (279) SOFOSBUVIR (260)

Which PEMBROLIZUMAB Alternatives Have Lower Hyperbilirubinaemia Risk?

PEMBROLIZUMAB vs PEMETREXED PEMBROLIZUMAB vs PEMIGATINIB PEMBROLIZUMAB vs PENICILLAMINE PEMBROLIZUMAB vs PENICILLIN PEMBROLIZUMAB vs PENICILLIN G

Related Pages

PEMBROLIZUMAB Full Profile All Hyperbilirubinaemia Reports All Drugs Causing Hyperbilirubinaemia PEMBROLIZUMAB Demographics