Does PERTUZUMAB Cause Hyperbilirubinaemia? 41 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 41 reports of Hyperbilirubinaemia have been filed in association with PERTUZUMAB (PERJETA). This represents 0.2% of all adverse event reports for PERTUZUMAB.
41
Reports of Hyperbilirubinaemia with PERTUZUMAB
0.2%
of all PERTUZUMAB reports
1
Deaths
17
Hospitalizations
How Dangerous Is Hyperbilirubinaemia From PERTUZUMAB?
Of the 41 reports, 1 (2.4%) resulted in death, 17 (41.5%) required hospitalization, and 3 (7.3%) were considered life-threatening.
Is Hyperbilirubinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 41 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Hyperbilirubinaemia?
METHOTREXATE (603)
RIBAVIRIN (560)
VINCRISTINE (479)
CYTARABINE (397)
PEGASPARGASE (349)
ACETAMINOPHEN (330)
CYCLOPHOSPHAMIDE (330)
DEXAMETHASONE (315)
CAPECITABINE (279)
SOFOSBUVIR (260)
Which PERTUZUMAB Alternatives Have Lower Hyperbilirubinaemia Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN